Shittake
Introducing Bio Optim's Shiitake Tincture — a concentrated extract of Lentinula edodes, a medicinal mushroom valued for its immune-supportive and metabolic benefits.
Why Shiitake — According to Science?
Shiitake mushrooms contain a range of bioactive compounds, including polysaccharides like lentinan, eritadenine, and polyphenols that support immune and cardiovascular function. Shiitake is one of the highest sources of Ergothioneine (EGT), which is referred to as a potent longevity amino acid, and Glutathione which is known as one of the most powerful anti-oxidants.
Mechanisms of Action:
• Immunomodulation – Lentinan (a β-glucan) enhances immune activity by stimulating macrophages, T-cells, and natural killer (NK) cells
• Cholesterol regulation – Eritadenine supports healthy lipid metabolism and may help reduce LDL cholesterol levels
• Antioxidant activity and DNA protection – Helps neutralize free radicals and reduce oxidative stress
Powerful Antioxidant & ROS Scavenger: EGT directly scavenges reactive oxygen species (ROS) and reactive nitrogen species (RNS), reducing oxidative stress
•Mitochondrial Protector: EGT accumulates in mitochondria—the energy powerhouse of cells—maintaining their integrity and supporting cellular energy homeostasis.
• Cytoprotection & Anti-inflammatory: It protects cells, such as erythrocytes, from damage caused by toxins or inflammation. It is known to modulate inflammation by interacting with signaling pathways (e.g., NRF2).
•Metal Chelation: EGT can chelate (bind) heavy metal ions, inhibiting their ability to cause damage.
•Cognitive & Cardiovascular Health: Higher serum levels of EGT are associated with reduced cardiovascular mortality, and it is studied for its role in mitigating neurodegenerative conditions like Alzheimer’s disease.
•Ergothioneine and Glutathione: act synergistically to reduce oxidative stress, with EGT notably protecting glutathione from oxidation and defending against age-related decline.
Physiological Benefits Observed in Studies:
• Strengthens immune defense and resilience
• Supports cardiovascular health and cholesterol balance
• Promotes gut and metabolic health
• Contributes to cellular protection and longevity
Why a Tincture Format?
Hydro-Ethanol extraction to provide the highest possible health boosting qualities, extracting water soluble beta-glucans and Ergothioneine, fat soluble triterpenes and sterols, all while maximising bioavailability.